Lung Cancer Screening: Reducing Lung Cancer Death

Introduction In this study, participants aged 55-74 years old, who had history of cigarette smoking >30 years or former smokers who had quit within 15 years were screened using low-dose CT (LDCT) or CXR, yearly for three consecutive years. Results Those who had yearly LDCT screening had higher number of lung cancer diagnosed when compared…… Continue reading Lung Cancer Screening: Reducing Lung Cancer Death

Head and Neck Cancer (HNC): Health Campaign

Make Sense Campaign (MSC) MSC is a health campaign in Europe to raise awareness in head and neck cancer (HNC). The focus of the campaign are disease prevention, identifying the signs and symptoms of HNC and to encourage seeking medical advice early. In early stage HNC, the survival rate is as high as 80-90% but…… Continue reading Head and Neck Cancer (HNC): Health Campaign

Colorectal Cancer (CRC): Benefits of Adjuvant Chemotherapy for Stage III CRC

Adjuvant treatment Adjuvant treatment is treatment given after primary treatment (eg. surgery). Types of adjuvant treatment for cancer are chemotherapy, radiotherapy, hormonal therapy, targeted therapy and biologic therapy.  Why is adjuvant treatment important? Even if the surgery was successful at removing all visible tumor, microscopic cancer cells that cannot be seen by surgeon can be…… Continue reading Colorectal Cancer (CRC): Benefits of Adjuvant Chemotherapy for Stage III CRC

Metastatic Colorectal Cancer (mCRC): Improving Survival (Left-sided vs Right-sided).

Introduction In metastatic colorectal cancer (mCRC), treatment in the first-line setting is very important to achieve longest survival. Combination chemotherapy, FOLFOX or FOLFIRI regimes, are the backbone for mCRC treatment. Biologic agents (anti-VEGR, anti-EGFR) were developed and used together with chemotherapy to improve survival. The first successful trial was combining bevacizumab with FOLFIRI, yielding around…… Continue reading Metastatic Colorectal Cancer (mCRC): Improving Survival (Left-sided vs Right-sided).

Early Breast Cancer: Importance of Hormonal Therapy in ER-positive Breast Cancer

A young lady in her early 40s had left breast cancer, pT2N2MO (stage III), ER positive, HER2 negative. She completed surgery, chemotherapy and radiotherapy. When I told her that she will need hormonal therapy for up to 10 years based on latest study, she said the study must be pharma-sponsored to encourage longer use of…… Continue reading Early Breast Cancer: Importance of Hormonal Therapy in ER-positive Breast Cancer