Colorectal Cancer (CRC): Benefits of Adjuvant Chemotherapy for Stage III CRC

Adjuvant treatment Adjuvant treatment is treatment given after primary treatment (eg. surgery, radiotherapy) to fully eradicate any remaining cancer cells. Types of adjuvant treatment for cancer are chemotherapy, radiotherapy, hormonal therapy, targeted therapy and biologic therapy.  Why is adjuvant treatment important? Even if the surgery was successful at removing all visible tumor, microscopic cancer cells…… Continue reading Colorectal Cancer (CRC): Benefits of Adjuvant Chemotherapy for Stage III CRC

Metastatic Colorectal Cancer (mCRC): Improving Survival (Left-sided vs Right-sided)

Introduction In metastatic colorectal cancer (mCRC), optimal treatment in the first-line setting is very important to achieve longer survival. Combination chemotherapy, FOLFOX/ XELOX and FOLFIRI/ XELIRI regimes, are the backbone for mCRC treatment. Improving survival Biologic agents (anti-VEGF, anti-EGFR) were later added to the combination chemotherapy regimes, resulting in longest survival ever seen for metastatic…… Continue reading Metastatic Colorectal Cancer (mCRC): Improving Survival (Left-sided vs Right-sided)