Colorectal Cancer (CRC): Benefits of Adjuvant Chemotherapy for Stage III CRC

Adjuvant treatment Adjuvant treatment is treatment given after primary treatment (eg. surgery). Types of adjuvant treatment for cancer are chemotherapy, radiotherapy, hormonal therapy, targeted therapy and biologic therapy.  Why is adjuvant treatment important? Even if the surgery was successful at removing all visible tumor, microscopic cancer cells that cannot be seen by surgeon can be…… Continue reading Colorectal Cancer (CRC): Benefits of Adjuvant Chemotherapy for Stage III CRC

Metastatic Colorectal Cancer (mCRC): Improving Survival (Left-sided vs Right-sided).

Introduction In metastatic colorectal cancer (mCRC), treatment in the first-line setting is very important to achieve longest survival. Combination chemotherapy, FOLFOX or FOLFIRI regimes, are the backbone for mCRC treatment. Biologic agents (anti-VEGR, anti-EGFR) were developed and used together with chemotherapy to improve survival. The first successful trial was combining bevacizumab with FOLFIRI, yielding around…… Continue reading Metastatic Colorectal Cancer (mCRC): Improving Survival (Left-sided vs Right-sided).