Living Longer: Stage 4 Stomach Cancer (1st line treatments)

In Malaysia, stomach cancer is the 8th most common cancer. Most stomach cancers were detected at late stage; III (25%) and IV (50%). The average/ median overall survival for stage 4 stomach cancer is not high but there had been incremental increases in average/ median overall survival throughout the years with chemotherapy and lately, with…… Continue reading Living Longer: Stage 4 Stomach Cancer (1st line treatments)

Lung Cancer: Clinical Research Data vs. Real World Data. Comparable?

In a conversation with my colleague, I was telling him that it would be nice to have more real world practice data. It would be interesting to see if results from real world practice is similar (or not) to those reported in clinical trials, which are conducted and tightly monitored for treatment effectiveness and patient…… Continue reading Lung Cancer: Clinical Research Data vs. Real World Data. Comparable?

Stage 4 Lung Cancer: How Long Can I Live? (2)

I saw a patient today with stage 4 lung cancer. He told me he has another 4-6 months to live, according to his doctor. Is it true? NO Nowadays, it is not just ‘stage 4’ determining the survival time. Let me elaborate. I will try to keep it simple. First, there is the histology of…… Continue reading Stage 4 Lung Cancer: How Long Can I Live? (2)

Stage 4 Lung Cancer: Targeted therapy & Immunotherapy. Which to Start?

Not all lung cancers are of the same type, stage or treated similarly. Targeted therapy For stage 4 lung adenocarcinoma (subset of NSCLC), further testing of EFGR and EML4-ALK mutation are routinely done in Malaysia. ROS1 rearranged mutation drivers is not routinely done although targetable treatment is available. Those with detected mutation/ presence of oncogenic…… Continue reading Stage 4 Lung Cancer: Targeted therapy & Immunotherapy. Which to Start?

Stage 4 Lung Cancer: How Long Will I Live? (1)

My new case today was a patient in his 50s, diagnosed with stage 4 lung cancer, which had spread to his liver and bones. He said he does not want any treatment and asked how long he can live. No treatment at all?! The benefits of chemotherapy treatment for stage 4 lung cancer had alredy…… Continue reading Stage 4 Lung Cancer: How Long Will I Live? (1)