Rectal Cancer: Most Important Decision

Rectal Cancer: Most Important Decision

A few weeks ago, my mom told me that she had per rectal bleeding. Expecting the worst, I maintained composure and remembered the first thing that I did. Actually, I was planning few things simultaneously for her such as getting an appointment for my mom for colonoscope, starting her on some medications but my first … Continue reading Rectal Cancer: Most Important Decision

Living Longer: Stage 4 Stomach Cancer (2nd line treatments)

Living Longer: Stage 4 Stomach Cancer (2nd line treatments)

Upon failure of first line treatment for advanced/ stage 4 stomach cancer, patients with good performance status will benefit from second line treatments. Which agent(s), chemotherapy/ biologic or immunotherapy offer longest median OS in this setting? Second-line Treatments Docetaxel: median OS of 5.2 months (COUGAR-02) - 8.4 months (Lee, 2005) Paclitaxel: median OS of 7.8 … Continue reading Living Longer: Stage 4 Stomach Cancer (2nd line treatments)

Living Longer: Stage 4 Stomach Cancer (1st line treatments)

Living Longer: Stage 4 Stomach Cancer (1st line treatments)

In Malaysia, stomach cancer is the 8th most common cancer. Most stomach cancers were detected at late stage; III (25%) and IV (50%). The average/ median overall survival for stage 4 stomach cancer is not high but there had been incremental increases in average/ median overall survival throughout the years with chemotherapy and lately, with … Continue reading Living Longer: Stage 4 Stomach Cancer (1st line treatments)

Lung Cancer: Clinical Research Data vs. Real World Data. Comparable?

Lung Cancer: Clinical Research Data vs. Real World Data. Comparable?

In a conversation with my colleague, I was telling him that it would be nice to have more real world practice data. It would be interesting to see if results from real world practice is similar (or not) to those reported in clinical trials, which are conducted and tightly monitored for treatment effectiveness and patient … Continue reading Lung Cancer: Clinical Research Data vs. Real World Data. Comparable?

Stage 4 Lung Cancer: How Long Can I Live? (2)

Stage 4 Lung Cancer: How Long Can I Live? (2)

I saw a patient today with stage 4 lung cancer. He told me he has another 4-6 months to live, according to his doctor. Is it true? No Nowadays, it is not just 'stage 4' determining the survival time. Let me elaborate. I will try to keep it simple. Histology First, there is the histology … Continue reading Stage 4 Lung Cancer: How Long Can I Live? (2)