Ca-125 in Ovarian Cancer: To Test or Not to Test?

I saw a patient yesterday with advanced ovarian cancer. She is young but unfortunately the disease had spread to her liver. Can tumor markers (Ca-125) help to detect her disease much earlier? Ovarian cancer One of the commonest cancer in women: Epithelial ovarian cancer formed the majority of the ovarian cancer cases (90%). The estimated lifetime…… Continue reading Ca-125 in Ovarian Cancer: To Test or Not to Test?

Early Breast Cancer: Will Treatments Affect My Chances To Get Pregnant?

A young patient in her 30s was recently diagnosed with early breast cancer (stage 2). She was not keen for further adjuvant treatment as she was worried that it might affect her fertility and chances to get pregnant. She didn’t even ask if it was safe for her to omit adjuvant treatment. There is one…… Continue reading Early Breast Cancer: Will Treatments Affect My Chances To Get Pregnant?

Rectal Cancer: Second Most Important Decision

Of course, before the surgery, other considerations such as pre-operative radiotherapy, pre-op chemo-radiotherapy, post-op radiotherapy, post-op chemo-radiotherapy, short course radiotherapy, long course radiotherapy and adjuvant chemotherapy all need to be discussed with your oncologist in order to get the best outcome. The second most important decision after finding yourself a good colorectal surgeon is deciding on…… Continue reading Rectal Cancer: Second Most Important Decision

Rectal Cancer: Most Important Decision

Few weeks ago, my mom told me that she had per rectal bleeding. Expecting the worst, I maintained composure and remembered the first thing that I did. Actually, I was planning few things simultaneously for her such as getting an appointment for my mom for colonoscope, starting her on some medications but my first instinct…… Continue reading Rectal Cancer: Most Important Decision

Living Longer: Stage 4 Stomach Cancer (2nd line treatments)

Upon failure of first line treatment for stage 4 stomach cancer, patients with good performance status will benefit from second line treatments. Which agents, chemotherapy/ targeted therapy offer longest median OS in this setting? Second-line Treatments Docetaxel: median OS of 5.2 months (COUGAR-02) – 8.4 months (Lee, 2005) Paclitaxel: median OS of 7.8 months (CCOG…… Continue reading Living Longer: Stage 4 Stomach Cancer (2nd line treatments)