Tag: advanced breast cancer

Living Longer: Advanced Breast Cancer (ABC) – HER2 over-expressed (2nd line treatments)

Living Longer: Advanced Breast Cancer (ABC) – HER2 over-expressed (2nd line treatments)

What Happen When First-Line Treatment Fails? In advanced or metastatic breast cancer, first-line treatment will fail after certain duration of time. This is because cancer cells developed resistance to the treatment and not because the treatment is ineffective. Life doesn't end when first-line treatment fails. We just continue fighting the cancer with other effective second-line … Continue reading Living Longer: Advanced Breast Cancer (ABC) – HER2 over-expressed (2nd line treatments)

Living Longer: Advanced Breast Cancer (ABC) – HER2 over-expressed (1st line treatments)

Living Longer: Advanced Breast Cancer (ABC) – HER2 over-expressed (1st line treatments)

Introduction HER2 over-expression constitutes around 20% of all breast cancer. Two different methods are being used to test for HER2 over-expression, immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) Immunohistochemistry (IHC); identifies HER2 expression on the cell surface, with a grading system of 0 to 3+ positive. tumors are classed as HER2-positive if they have … Continue reading Living Longer: Advanced Breast Cancer (ABC) – HER2 over-expressed (1st line treatments)