Better Practice: No More Surgery for Stage 4 Kidney Cancer?!

Introduction The summary for the above Carmena trial; randomised phase III clinical trial to study if patients with advanced kidney cancer can avoid surgery altogether without compromising survival. Current standard of care: nephrectomy for patients with kidney cancer who have metastatic disease when the cancer is first diagnosed, followed by targeted therapy; affecting 20% of patients (huge…… Continue reading Better Practice: No More Surgery for Stage 4 Kidney Cancer?!

Living Longer: Advanced Stage Liver Cancer (BCLC C)

Introduction Unfortunately, more than 2/3 of liver cancer patients are diagnosed at advanced stage liver cancer (BCLC C). Advanced stage liver cancer (BCLC C) consist(s) of: invasion into major liver blood vessels or/ and spread beyond the liver (lung, lymph nodes). Patients in BCLC C group will benefit from systemic treatment (also suitable for BCLC…… Continue reading Living Longer: Advanced Stage Liver Cancer (BCLC C)

Stage 4 Lung Cancer: Targeted therapy & Immunotherapy. Which to Start?

Not all lung cancers are the same type. Not all lung cancers are of same stage. Not all lung cancers are treated with similar treatment. Targeted therapy For stage 4 lung adenocarcinoma (subset of NSCLC), further testing of EFGR and EML4-ALK mutation are routinely done in Malaysia. ROS1 rearranged mutation drivers is not routinely done…… Continue reading Stage 4 Lung Cancer: Targeted therapy & Immunotherapy. Which to Start?