Tag: targeted therapy

Better Practice: No More Surgery for Stage 4 Kidney Cancer?!

Better Practice: No More Surgery for Stage 4 Kidney Cancer?!

Introduction The summary for the above Carmena trial; randomised phase III clinical trial to study if patients with advanced kidney cancer can avoid surgery altogether without compromising survival. Current standard of care: nephrectomy for patients with kidney cancer who have metastatic disease when the cancer is first diagnosed, followed by targeted therapy; affecting 20% of patients (huge … Continue reading Better Practice: No More Surgery for Stage 4 Kidney Cancer?!

Living Longer: Advanced Stage Liver Cancer (BCLC C)

Living Longer: Advanced Stage Liver Cancer (BCLC C)

Introduction Unfortunately, more than 2/3 of liver cancer patients are diagnosed at advanced stage liver cancer (BCLC C). Advanced stage liver cancer (BCLC C) consist(s) of: invasion into major liver blood vessels or/ and spread beyond the liver (lung, lymph nodes). Patients in BCLC C group will benefit from systemic treatment (also suitable for BCLC … Continue reading Living Longer: Advanced Stage Liver Cancer (BCLC C)

Stage 4 Lung Cancer: Targeted therapy & Immunotherapy. Which to Start?

Stage 4 Lung Cancer: Targeted therapy & Immunotherapy. Which to Start?

Not all lung cancers are of the same type, stage or treated similarly. Targeted therapy For stage 4 lung adenocarcinoma (subset of NSCLC), further testing of EFGR and EML4-ALK mutation are routinely done in Malaysia. ROS1 rearranged mutation driver testing is not routinely done although targetable treatment is available. (free testing now available in Malaysia) … Continue reading Stage 4 Lung Cancer: Targeted therapy & Immunotherapy. Which to Start?